Yingjie Fu , He Wang

Harbin Maternal and Child Health and Family Planning Service Center of Heilongjiang, Heilongjiang, China
Author    Correspondence author
Cancer Genetics and Epigenetics, 2019, Vol. 7, No. 7   doi: 10.5376/cge.2019.07.0007
Received: 07 Sep., 2019    Accepted: 24 Sep., 2019    Published: 30 Sep., 2019

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Fu Y.J., and Wang H., 2019, Clinical observation of cinnamon Twig and Poria decoction in combination with mifepristone in the treatment of uterine fibroids, Cancer Genetics and Epigenetics, 7(7): 23-26 (doi: 10.5376/cge.2019.07.0007)

To investigate the efficacy of mifepristone + cinnamon twig and poria decoction in patients with uterine fibroids. A total of 100 patients with uterine fibroids were enrolled in this study, who were treated in our hospital from March 2017 to October 2018. They were randomly divided into two groups: control group (n=50) and treatment group (n=50). The patients in the treatment group were treated with mifepristone + cinnamon twig and poria decoction and those in the control group received mifepristone alone. The sex hormone levels, treatment outcome and uterine fibroid volume were summarized in the two groups. Progesterone level in the treatment group was lower than that in the control group. The difference was statistically significant (P＜0.05). The level of follicle stimulating hormone in the treatment group was lower than in the control group. The difference was statistically significant (P＜0.05). The estradiol level in the treatment group was lower than that in the control group. The difference was statistically significant (P＜0.05). The level of luteinizing hormone in the treatment group was lower than that in the control group. The difference was statistically significant (P＜0.05). The total response rate of the treatment group was higher than that of the control group. The difference was statistically significant (P＜0.05).The sizes of uterine fibroids in the treatment group were smaller than those in the control group. The difference was statistically significant (P＜0.05). The response rate of mifepristone in combination with cinnamon twig and poria decoction is high in patients with uterine fibroids, which can significantly improve the sex hormone levels of patients, and remarkably reduce the volume of uterine fibroids.

Uterine fibroids/uterine myoma; Mifepristone; Cinnamon twig and poria decoction; Efficacy/treatment outcome